Nitric Acid → HCID 12831512, compound

HRID 615169Notes

Reaction equation

HRID 615169 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[N:9]=[C:10]3[N:14]([CH:15]=2)[C:13]2[CH:16]=[CH:17][CH:18]=[CH:19][C:12]=2[S:11]3)=[CH:4][CH:3]=1.[N+:20]([O-])([OH:22])=[O:21]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[N:9]=[C:10]3[N:14]([C:15]=2[N+:20]([O-:22])=[O:21])[C:13]2[CH:16]=[CH:17][CH:18]=[CH:19][C:12]=2[S:11]3)=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 944Nitric AcidHCID 667714HCID 667714, compound

Product 1

HCID 12831512HCID 12831512, compound

Procedure

After cooling 30 ml of fuming nitric acid to -35° to -45° C., 3 g of 2-(p-chlorophenyl)imidazo[2,1-b]benzothiazole was gradually added thereto. The reaction mixture was poured into ice water and the crystals which formed were recovered by filtration and recrystallized from acetic acid to provide 2.2 g of 2-(p-chlorophenyl)-3-nitroimidazo[2,1-b]benzothiazole.

Workup

  1. customthe crystals which formed
  2. filtrationwere recovered by filtration
  3. customrecrystallized from acetic acid

Sources & evidence

ORD record
ord-648f4173f1af42f1a66cdfd15544ba51
Source dataset
uspto-grants-1985_02
Patent number
US04497817

Reaction notes

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