Potassium Carbonate → HCID 20429506、化合物

関与物質

反応手順

A mixture of 98.4 g (0.45 mole) of 7-chlorodibenzofuran-3-ol, 200 ml of methyl ethyl ketone, 93 g (0.67 mole) of potassium carbonate and 283 g (1.4 moles) of dibromopropane was refluxed for 24 hours, while stirring. The inorganic precipitate was filtered off under suction, the filtrate was evaporated down under reduced pressure, the residue was dissolved in 500 ml of methylene chloride, and the solution was washed with 100 ml of water, 100 ml of 2N sodium hydroxide solution and 100 ml of water in succession, dried over sodium sulfate and evaporated down under reduced pressure. The solid residue was left to stand with 30 ml of pentane at 0° C. for 30 minutes, after which it was filtered off under suction and washed with 30 ml of cold n-pentane. 77 g (50% of theory) of pure 1-bromo-3-(7-chlorodibenzofuran-3-yloxy)-propane of melting point 83°-85° C. were obtained.

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