2-Chlorobenzoyl isocyanate → HCID 13229715, compound

Participants

Reaction Conditions

Reaction Steps

A solution of 50 g of 2-chlorobenzoyl isocyanate in 50 ml of dry toluene was added to a stirred solution of 60 g of N-[4-(trifluoromethoxy)phenyl]-2-nitrobenzenesulphenamide in 100 ml of the same solvent. The reaction was slightly exothermic, reaching a maximum temperature of 35° C. After 4 days at room temperature, the reaction mixture was cooled to -5° C. and the crystalline cake of product was broken up under cold toluene, filtered, washed with toluene followed by cold light petroleum (b.p. 40°-60° C.) and dried at 40° C. under reduced pressure, to give 1, as pale yellow crystals, m.p. 155°-158° C. (with decomposition).

Provenance & Evidence