2,6-Difluorobenzoyl isocyanate → HCID 13229719, compound

Participants

Reaction Conditions

Reaction Steps

A solution of 1.8 g of 2,6-difluorobenzoyl isocyanate in 15 ml of dry toluene was added over 15 minutes to a stirred solution of 2.8 g of N-(4-chlorophenyl)-2-nitrobenzenesulphenamide in 35 ml of the same solvent at room temperature. After stirring overnight, the reaction was incomplete. A few drops of triethylamine were added, and after a further 24 hours, the reaction mixture was cooled to -5° C. and filtered, and the pale yellow product was washed with cold toluene. Traces of toluene were removed by drying under reduced pressure at about 40° C. for 3 days, to give 5, as a solid, m.p.: 176°-178° C.

Provenance & Evidence