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N-(2-Chloroethyl)dibenzylamine → 3-(2-Dibenzylaminoethoxy)salicylic acid methyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | N-(2-Chloroethyl)dibenzylamine | HCID 5820 | — |
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | Methyl 2,3-Dihydroxybenzoate | HCID 75484 | — |
| 溶媒 | Acetonitrile | HCID 6342 | — |
| 生成物 | 3-(2-Dibenzylaminoethoxy)salicylic acid methyl ester | HCID 53929446 | — |
反応手順
2,3-dihydroxybenzoic acid methyl ester is reacted in the presence of potassium carbonate in acetonitrile with 1.1 equivalents of 1-dibenzylamino-2-chloroethane for 18 hours at 82°. The crude 3-(2-dibenzylaminoethoxy)-salicylic acid methyl ester obtained after working up is put to further use without further purification.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04497813 |
| 出典データセット | uspto-grants-1985_02 |
| ORD ID | ord-bfd4af106aa846cdabaa6603de804460 |
| 出典メモ | uspto-grants-1985_02 |