Acetone → HCID 13454039, compound

HRID 615282Notes

Reaction equation

HRID 615282 reaction equation
[NH2:1][C:2]1[NH:3][C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=1.[CH2:11]([N:14]=[C:15]=[O:16])[CH2:12][CH3:13].[CH3:17][C:18]([CH3:20])=O>>[CH3:17][C:18]1([CH3:20])[N:14]([CH2:11][CH2:12][CH3:13])[C:15](=[O:16])[N:6]2[C:2]([N:3]([C:15]([NH:14][CH2:11][CH2:12][CH3:13])=[O:16])[C:4]3[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=32)=[N:1]1

Participants

4

Reactant 3

HCID 180AcetoneHCID 136242-AminobenzimidazoleHCID 61033Propyl isocyanate

Product 1

HCID 13454039HCID 13454039, compound

Procedure

The subject compound was prepared by reaction of 2-aminobenzimidazole, acetone and propyl isocyanate with workup all essentially as described in the first paragraph of Example 1. The product was purified by column chromatography on silica, eluting with chloroform, giving, on evaporation, white crystals, mp 72°-74° C. The confirmatory elemental analysis is shown in Table III.

Workup

  1. customThe product was purified by column chromatography on silica
  2. washeluting with chloroform
  3. customgiving, on evaporation, white crystals, mp 72°-74° C

Sources & evidence

ORD record
ord-87f6bf32f4a84f788f0f13ae36a5f73c
Source dataset
uspto-grants-1985_02
Patent number
US04498920

Reaction notes

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