Acetone → 1,3,5-Triazino(1,2-a)benzimidazol-4(1H)-one, 3-butyl-2,3-dihydro-2,2-dimethyl-

HRID 615284Notes

Reaction equation

HRID 615284 reaction equation
[NH2:1][C:2]1[NH:3][C:4]2[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=2[N:6]=1.[CH2:11]([N:15]=[C:16]=[O:17])[CH2:12][CH2:13][CH3:14].[CH3:18][C:19]([CH3:21])=O>>[CH2:11]([N:15]1[C:16](=[O:17])[N:6]2[C:2](=[N:3][C:4]3[CH:10]=[CH:9][CH:8]=[CH:7][C:5]=32)[NH:1][C:19]1([CH3:21])[CH3:18])[CH2:12][CH2:13][CH3:14]

Participants

4

Reactant 3

HCID 180AcetoneHCID 8110Butyl isocyanateHCID 136242-Aminobenzimidazole

Product 1

HCID 1591051,3,5-Triazino(1,2-a)benzimidazol-4(1H)-one, 3-butyl-2,3-dihydro-2,2-dimethyl-

Procedure

The title compound was prepared from 2-aminobenzimidazole, acetone, and n-butyl isocyanate, conducting the initial condensation and subsequent base hydrolysis of the intermediate 10-N-butylcarbamoyl precursor as described in Example 1. The solid product had mp 142°-149° C. (dec.). The confirmatory elemental analysis is shown in Table III.

Workup

  1. customcondensation and subsequent base hydrolysis of the intermediate 10-N-butylcarbamoyl precursor

Sources & evidence

ORD record
ord-e4c6d86fd43a4c0d8791ca977bebd110
Source dataset
uspto-grants-1985_02
Patent number
US04498920

Reaction notes

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