Ethyl isocyanate → 1,3,5-Triazino(1,2-a)benzimidazole-10(2H)-carboxamide,N-ethyl-3,4-dihydro-2,2,3-trimethyl-4-oxo-

HRID 615285Notes

Reaction equation

HRID 615285 reaction equation
[CH3:1][C:2]1([CH3:17])[N:10]([CH3:11])[C:9](=[O:12])[N:8]2[C:4](=[N:5][C:6]3[CH:16]=[CH:15][CH:14]=[CH:13][C:7]=32)[NH:3]1.[CH2:18]([N:20]=[C:21]=[O:22])[CH3:19]>>[CH2:18]([NH:20][C:21]([N:5]1[C:6]2[CH:16]=[CH:15][CH:14]=[CH:13][C:7]=2[N:8]2[C:9](=[O:12])[N:10]([CH3:11])[C:2]([CH3:17])([CH3:1])[N:3]=[C:4]12)=[O:22])[CH3:19]

Participants

3

Reactant 2

HCID 8022Ethyl isocyanateHCID 1591201,2-dihydro-2,2,3-trimethyl-1,3,5-triazino[1,2-a]benzimidazol-4(3H)-one

Product 1

HCID 1591071,3,5-Triazino(1,2-a)benzimidazole-10(2H)-carboxamide,N-ethyl-3,4-dihydro-2,2,3-trimethyl-4-oxo-Yield 96%

Procedure

The title compound was prepared by reaction of 1,2-dihydro-2,2,3-trimethyl-1,3,5-triazino[1,2-a]benzimidazol-4(3H)-one (see Example 1 (B)) with ethyl isocyanate according to the general procedure of Example 10. The product, mp 127°-131° C., was obtained as a white solid in 96% yield. The confirmatory elemental analysis is shown in Table III.

Workup

  1. customThe product, mp 127°-131° C., was obtained as a white solid in 96% yield

Sources & evidence

ORD record
ord-158113253f1849f7b00db7ce6cb7cf2b
Source dataset
uspto-grants-1985_02
Patent number
US04498920

Reaction notes

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