Methyl Isobutyl Ketone → HCID 135797537, compound

Participants

Reaction Steps

2-Aminobenzimidazole, methyl isobutyl ketone and ethyl isocyanate were reacted as in Example 26 using an equal volume of THF as cosolvent with the excess ketone. Working up the reaction mixture gave a crude fraction of the 10-N-methylcarbamoyl derivative of the title compound which was not purified but hydrolyzed by the 10% NaOH-THF procedure of Example 1, paragraph 2. The title compound was obtained as a solid, mp 150°-157° C. The confirmatory elemental analysis is shown in Table III.

Provenance & Evidence