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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 615342Generated: October 29, 2026

Dimethyl acetylenedicarboxylate → 3-(1-Pyrrolidinyl)-2,7-cycloheptadiene-1,2-dicarboxylic acid, dimethyl ester

https://huagongshe.com/reaction/615342

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethyl acetylenedicarboxylateHCID 12980—
ReactantPyrrolidine, 1-(1-cyclopenten-1-yl)-HCID 81570—
Product3-(1-Pyrrolidinyl)-2,7-cycloheptadiene-1,2-dicarboxylic acid, dimethyl esterHCID 12404519—

Reaction Steps

1-(1-Cyclopenten-1-yl)pyrrolidine and 2-butynedioic acid, dimethyl ester are reacted according to the procedure set forth in J.O.C., Vol. 28, p. 1464 (1963) to yield 3-(1-pyrrolidinyl)-2,7-cycloheptadiene-1,2-dicarboxylic acid, dimethyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04499079
Source datasetuspto-grants-1985_02
ORD IDord-e6d9da2b50e54eb7a21c3f62ff2ee73b
Source noteuspto-grants-1985_02