Dimethyl N-cyanodithioiminocarbonate → N-cyano-N'[2-(2-pyridylmethylthio)ethyl]-S-methylisothiourea

HRID 615367Notes

Reaction equation

HRID 615367 reaction equation
[NH2:1][CH2:2][CH2:3][S:4][CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][N:7]=1.[CH3:12][S:13][C:14](=[N:17][C:18]#[N:19])SC>>[C:18]([NH:17][C:14](=[N:1][CH2:2][CH2:3][S:4][CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][N:7]=1)[S:13][CH3:12])#[N:19]

Participants

3

Reactant 2

HCID 66289Dimethyl N-cyanodithioiminocarbonateHCID 128894012-((2-Aminoethyl)thiomethyl)pyridine

Product 1

HCID 12889408N-cyano-N'[2-(2-pyridylmethylthio)ethyl]-S-methylisothiourea

Procedure

The reaction of 2-((2-aminoethyl)thiomethyl)pyridine with dimethylcyanodithioimidocarbonate by a method similar to that described in Example (3d) afforded N-cyano-N'-[2-(2-pyridylmethylthio)ethyl]-S-methylisothiourea, m.p. 85°-88°. (from isopropyl alcohol-ether)

Sources & evidence

ORD record
ord-607535de103645f9b26fbdfeef392e90
Source dataset
uspto-grants-1985_02
Patent number
US04499101

Reaction notes

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