Acetic Anhydride → HCID 54002553, compound

HRID 615375Notes

Reaction equation

HRID 615375 reaction equation
[OH:1][N:2]=[C:3]([CH:5]1[CH2:13][C:12]2[C:7](=[CH:8][C:9]([O:16][CH3:17])=[C:10]([O:14][CH3:15])[CH:11]=2)[CH2:6]1)[NH2:4].[C:18](OC(=O)C)(=[O:20])[CH3:19]>>[C:18]([O:1][N:2]=[C:3]([CH:5]1[CH2:13][C:12]2[C:7](=[CH:8][C:9]([O:16][CH3:17])=[C:10]([O:14][CH3:15])[CH:11]=2)[CH2:6]1)[NH2:4])(=[O:20])[CH3:19]

Participants

3

Reactant 2

HCID 7918Acetic AnhydrideHCID 133251HCID 133251, compound

Product 1

HCID 54002553HCID 54002553, compound

Procedure

A suspension of 6.6 g (28 mmol) 2,3-dihydro-N'-hydroxy-5,6-dimethoxy-1H-indene-2-carboximidamide was stirred in 50 ml of acetic acid anhydride for 1 hour at room temperature. The suspension was subsequently poured out into 500 ml of ice water and, after 2 hours stirring, was drawn off and washed to neutral with water.

Workup

  1. washwashed to neutral with water

Sources & evidence

ORD record
ord-8aaddd0a43cd450f92d171bc3d88146e
Source dataset
uspto-grants-1985_02
Patent number
US04499105

Reaction notes

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