HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethylamine → 4-(2-Chlorophenyl)-N,N-diethylthieno[3,2-c]pyridine-6-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethylamine | HCID 8021 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Ethyl chloroformate | HCID 10928 | — |
| Reactant | 4-(2-Chlorophenyl)thieno[3,2-c]pyridine-6-carboxylic acid | HCID 13272386 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 4-(2-Chlorophenyl)-N,N-diethylthieno[3,2-c]pyridine-6-carboxamide | HCID 13272383 | 60.8% |
Reaction Steps
Operations are carried out as for example 7, starting from 2.9 g of 4-(2-chloro phenyl) thieno[3,2-c]pyridine 6-carboxylic acid, 1.17 g of triethylamine, 1.25 g of ethyl chloroformate and 0.94 g of diethylamine in 100 ml of chloroform. 2.1 g of N,N-diethyl 4-(2-chloro phenyl) thieno[3,2-c]pyridine 6-carboxamide, melting at 119° C., are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04499094 |
| Source dataset | uspto-grants-1985_02 |
| ORD ID | ord-41fd492fc2d54a34a2587bc607613c18 |
| Source note | uspto-grants-1985_02 |