Formaldehyde → HCID 86736903, compound

Participants

Reaction Steps

Methyl α-chloropalmitate (6.1 g, 0.02 m) was dissolved in 40 ml DMF and treated with lithium methoxide (0.84, 0.022 m) followed by portionwise addition of paraformaldehyde (0.63 g, 0.021 m) over a period of about eight hours. The reaction mixture was stirred at room temperature overnight. The reaction was worked up by neutralization to pH 7 with methanol-HCl, evaporation of the DMF; the residue was dissolved in ether and filtered. Evaporation of the ether led to 99.5 percent recovery of methyl 2-tetradecylglycidate as an oil. Crystallization from methanol (twice) gave material with a melting point of 40°-42°.

Provenance & Evidence