Formaldehyde → HCID 86736903, compound

Participants

Reaction Steps

Methyl α-chloropalmitate (61 g, 0.20 m) was dissolved in 400 ml DMF and treated with lithium methoxide (8.35 g, 0.22 m) followed by portionwise addition of paraformaldehyde (6.3 g, 0.21 m) over a period of about eight hours. The reaction was stirred overnight, 12 hours after complete addition, at room temperature. It was worked up by extraction with hexane; the hexane was dried and evaporated to yield 53 g (89 percent) methyl 2-tetradecylglycidate (97 percent purity by glc) with m.p. 45°-48° C. after recrystallization from methanol.

Provenance & Evidence