Methanol → Methyl 4-methylbenzoate

HRID 615489Notes

Reaction equation

HRID 615489 reaction equation
[CH3:1][C:2]1[CH:10]=[CH:9][C:5]([C:6](Cl)=[O:7])=[CH:4][CH:3]=1.[CH3:11][OH:12]>>[CH3:1][C:2]1[CH:10]=[CH:9][C:5]([C:6]([O:12][CH3:11])=[O:7])=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 887MethanolHCID 134054-Methylbenzoyl Chloride

Product 1

HCID 7455Methyl 4-methylbenzoate

Procedure

To 200 ml of methanol at 0° was added, with stirring, 48.4 g (0.312 mole) of 4-methylbenzoyl chloride over 20 minutes. Following the addition, the reaction mixture was stirred at room temperature for one hour. The methanol was evaporated and the residue was distilled to give 43 g of the title compound as a colorless liquid: boiling point 103°-108° C. at 20 mm of Hg.

Workup

  1. additionthe addition
  2. stirringthe reaction mixture was stirred at room temperature for one hour
  3. customThe methanol was evaporated
  4. distillationthe residue was distilled

Sources & evidence

ORD record
ord-17474f3e5cbf45168c85d4b2f9e216bf
Source dataset
uspto-grants-1985_02
Patent number
US04499299

Reaction notes

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