HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Lutidine → 3-Methoxy-4-methylbenzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Lutidine | HCID 7937 | — |
| Reactant | 3-Methoxy-4-methylbenzoyl chloride | HCID 2759584 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3-Methoxy-4-methylbenzaldehyde | HCID 4715095 | — |
Reaction Steps
A mixture of 5.0 g (27.08 mmol) of 3-methoxy-4-methylbenzoyl chloride, 4.0 ml (34.34 mmol) of 2,6-lutidine and 400 mg of 10% palladium on carbon in 40 ml of THF was rapidly stirred under an atmosphere of hydrogen until no more hydrogen was taken up. Filtration and extraction with ethyl acetate gave title compound as a light yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04499299 |
| Source dataset | uspto-grants-1985_02 |
| ORD ID | ord-2206dd495341406a86ac888b68687a31 |
| Source note | uspto-grants-1985_02 |