Potassium Hydroxide → HCID 20407007, compound

HRID 615541Notes

Reaction equation

HRID 615541 reaction equation
Cl[CH2:2][CH2:3][CH:4]([CH3:19])[C:5]([NH:7][C:8]1[CH:12]=[C:11]([C:13]([CH3:18])([CH3:17])[CH2:14][CH2:15][CH3:16])[O:10][N:9]=1)=[O:6].[OH-].[K+]>O.C(O)C>[CH3:17][C:13]([C:11]1[O:10][N:9]=[C:8]([N:7]2[CH2:2][CH2:3][CH:4]([CH3:19])[C:5]2=[O:6])[CH:12]=1)([CH3:18])[CH2:14][CH2:15][CH3:16]

Participants

5

Reactant 2

HCID 14797Potassium HydroxideHCID 20407026HCID 20407026, compound

Product 1

HCID 20407007HCID 20407007, compoundYield 20%

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 962WaterSolvent

Procedure

1-[5-(1,1-Dimethylbutyl)-3-isoxazolyl]-3-methyl-2-pyrrolidinone was prepared by reacting 17.2 g of 4-chloro-N-[5-(1,1-dimethylbutyl)-3-isoxazolyl]-2-methylbutanamide with 6.72 g of potassium hydroxide in 30 ml water and 75 ml ethanol by the general method of Example 3. Weight 4 g (Yield 20%). mp 30°-31° C.

Sources & evidence

ORD record
ord-3a8dc7655aa34df981c452541e0fe34c
Source dataset
uspto-grants-1985_02
Patent number
US04500343

Reaction notes

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