Pyridinium chloride → HCID 53646608, compound
Reaction equation
[CH3:1][N:2]([CH3:18])[CH2:3][CH2:4][CH:5]([CH:15]1[CH2:17][CH2:16]1)[O:6][C:7]1[CH:12]=[CH:11][C:10]([O:13]C)=[CH:9][CH:8]=1.Cl.N1C=CC=CC=1>>[CH3:18][N:2]([CH3:1])[CH2:3][CH2:4][CH:5]([CH:15]1[CH2:16][CH2:17]1)[O:6][C:7]1[CH:8]=[CH:9][C:10]([OH:13])=[CH:11][CH:12]=1Participants
3
Procedure
A mixture of 1 g of 1-dimethylamino-3-cyclopropyl-3-p-methoxyphenoxy-propane and 1 g of pyridine hydrochloride is stirred for 3 hours at 160°. After the customary working up, 1-dimethylamino-3-cyclopropyl-3-p-hydroxyphenoxy-propane is obtained.
Sources & evidence
- ORD record
- ord-531b40e90d1d4346a6fd1e483de1ab36
- Source dataset
- uspto-grants-1985_02
- Patent number
- US04500541
Reaction notes
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