Isopropylamine → HCID 86051403, compound

HRID 615622Notes

Reaction equation

HRID 615622 reaction equation
BrCCC1C=C([Cl:10])C=[CH:6][C:5]=1[O:11][C:12]1[CH:17]=[CH:16][C:15]([Cl:18])=[CH:14][C:13]=1CCBr.[CH:22]([NH2:25])([CH3:24])[CH3:23]>>[ClH:10].[Cl:18][C:15]1[CH:14]=[CH:13][C:12]([O:11][CH2:5][CH2:6][NH:25][CH:22]([CH3:24])[CH3:23])=[CH:17][CH:16]=1

Participants

3

Reactant 2

HCID 6363IsopropylamineHCID 57126877HCID 57126877, compound

Product 1

HCID 86051403HCID 86051403, compound

Procedure

Following the procedure of Preparation 11, 2-bromoethyl-4-chlorophenyl ether and isopropyl amine (excess) were reacted and the reaction mixture processed to give an oil, the free base of the title compound. A portion of the oil was reacted with ethereal hydrogen chloride to give the hydrochloride salt, m.p. 162°-164° C. in 69.3% yield.

Workup

  1. customwere reacted
  2. customto give an oil

Sources & evidence

ORD record
ord-8884f39707fb490787f22a29c3714e7b
Source dataset
uspto-grants-1985_02
Patent number
US04500529

Reaction notes

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