Isopropylamine → HCID 86051483, compound

HRID 615625Notes

Reaction equation

HRID 615625 reaction equation
BrCCC1C=[CH:8][C:7]([O:10][C:11]2[CH:16]=[CH:15][C:14](CCBr)=[C:13]([Cl:20])[C:12]=2[Cl:21])=C(Cl)C=1Cl.[CH:24]([NH2:27])([CH3:26])[CH3:25]>>[ClH:20].[Cl:21][C:12]1[C:13]([Cl:20])=[CH:14][CH:15]=[CH:16][C:11]=1[O:10][CH2:7][CH2:8][NH:27][CH:24]([CH3:26])[CH3:25]

Participants

3

Reactant 2

HCID 6363IsopropylamineHCID 57320665HCID 57320665, compound

Product 1

HCID 86051483HCID 86051483, compoundYield 62.7%

Procedure

Following the procedure of Example 11, 2-bromoethyl-2,3-dichlorophenyl ether was reacted with isopropyl amine (excess) and the reaction mixture processed to give an oil, the free base of the title compound. A portion of the oil was reacted with ethereal hydrogen chloride salt, m.p. 161°-163.5° C. in 62.7% yield.

Workup

  1. customto give an oil

Sources & evidence

ORD record
ord-206ddd90928d45f9afbc017a5ed959af
Source dataset
uspto-grants-1985_02
Patent number
US04500529

Reaction notes

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