Water → HCID 20256351, compound

HRID 615637Notes

Reaction equation

HRID 615637 reaction equation
C(O)(=O)/C=C\C(O)=[O:5].[Cl:9][C:10]1[CH:11]=[C:12]([CH:28]=[C:29]([Cl:31])[CH:30]=1)[O:13][CH2:14][CH2:15][N:16]([CH:25]([CH3:27])[CH3:26])[C:17]([NH:19][CH2:20][CH2:21][N:22]([CH3:24])[CH3:23])=[O:18].[OH-].[Na+].O>>[OH2:5].[Cl:9][C:10]1[CH:11]=[C:12]([CH:28]=[C:29]([Cl:31])[CH:30]=1)[O:13][CH2:14][CH2:15][N:16]([CH:25]([CH3:27])[CH3:26])[C:17]([NH:19][CH2:20][CH2:21][N:22]([CH3:23])[CH3:24])=[O:18]

Participants

4

Reactant 3

HCID 962WaterHCID 14798Sodium HydroxideHCID 70472636HCID 70472636, compound

Product 1

HCID 20256351HCID 20256351, compound

Procedure

A solution of N-[2-(3,5-dichlorophenoxy)ethyl]-N'-[2-(dimethylamino)ethyl]-N-(1-methylethyl)urea Maleate [1:1], from Example 3A, was basified with 2M sodium hydroxide solution and extracted with methylene chloride. The methylene chloride layer was dried over magnesium sulfate and evaporated under vacuum to give an oil. Nuclear magnetic resonance measurements showed the product had 1/2 equivalent of water present.

Workup

  1. extractionextracted with methylene chloride
  2. dry with materialThe methylene chloride layer was dried over magnesium sulfate
  3. customevaporated under vacuum
  4. customto give an oil

Sources & evidence

ORD record
ord-4ea46d9294f24e02b5297533275d7655
Source dataset
uspto-grants-1985_02
Patent number
US04500529

Reaction notes

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