Methacrylic Acid → (3-Formyl-4-hydroxyphenyl)methyl 2-methylprop-2-enoate

Participants

Reaction Steps

5-Chloromethylsalicylaldehyde (34 g) (prepared by the method of Angyal et al., J. Chem. Soc. 2141, (1950)) was added to a stirred mixture of acetone (250 ml), sodium hydrogen carbonate (33.6 g), and methacrylic acid (34.4 g) and the mixture was stirred under reflux for 21/2 hours. Addition of the mixture to ice water gave a grey precipitate which was collected, washed with water, dried, and crystallized from light petroleum (b.p. 60°-80° C.). Yield 32.1 g, m.p. 82-4.

Provenance & Evidence