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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 615654Generated: November 1, 2026

Hydrochloric Acid → N-[4-(Hexadecyloxy)-2-hydroxyphenyl]acetamide

https://huagongshe.com/reaction/615654

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantEthanolHCID 702—
ReactantHCID 12886752HCID 12886752—
SolventWaterHCID 962—
ProductN-[4-(Hexadecyloxy)-2-hydroxyphenyl]acetamideHCID 13765207—

Reaction Steps

A mixture of 111 g of 6-hexadecyloxy-2-methylbenzoxazole, 1,300 ml of ethanol, 110 ml of 33% hydrochloric acid and 550 ml of water was stirred at 55°-60° C. for 4 hours. The reaction solution was cooled to precipitate crystals, and the crystals were collected by filtration. 113 g of 2-acetylamino-5-hexadecyloxyphenol was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04500626
Source datasetuspto-grants-1985_02
ORD IDord-a1620efecd7841509d4cb8d7207d550e
Source noteuspto-grants-1985_02