Sodium Hydroxide → HCID 54300440, compound

HRID 615744Notes

Reaction equation

HRID 615744 reaction equation
[O:1]1[C:6]([C:7](=[N:13][O:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])[C:8]([O:10]CC)=[O:9])=[CH:5][S:4][CH2:3][CH2:2]1.[OH-].[Na+]>CO>[O:1]1[C:6]([C:7](=[N:13][O:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH3:20])[C:8]([OH:10])=[O:9])=[CH:5][S:4][CH2:3][CH2:2]1

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 53819662HCID 53819662, compound

Product 1

HCID 54300440HCID 54300440, compoundYield 25.4%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Ethyl 2-(2,3-dihydro-1,4-oxathiin-6-yl)-2-n-hexyloxyiminoacetate (mixture of syn isomer and anti isomer, 186.8 g.), 1N aqueous solution of sodium hydroxide (472 ml.) and methanol (1.8 l.) were stirred at room temperature for 35 minutes and the insoluble substance was removed by filtration. The filtrate was stirred at room temperature for 43 hours and treated in a similar manner to that of Example I-(iii) to give 2-(2,3-dihydro-1,4-oxathiin-6-yl)-2-n-hexyloxyiminoacetic acid (syn isomer, 43 g.).

Workup

  1. customthe insoluble substance was removed by filtration
  2. additiontreated in a similar manner to that of Example I-(iii)

Sources & evidence

ORD record
ord-32d2cd5147a54b23bef3a71a779bb366
Source dataset
uspto-grants-1985_02
Patent number
US04500709

Reaction notes

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