HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → 2-Phenoxycarbonylaminothiazolo[4,5-c]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Phenyl chloroformate | HCID 15891 | — |
| Reactant | (1,3)Thiazolo(4,5-c)pyridin-2-amine | HCID 14252938 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 2-Phenoxycarbonylaminothiazolo[4,5-c]pyridine | HCID 15593549 | 71.1% |
Reaction Steps
To a mixture of 2-aminothiazolo[4,5-c]pyridine (302 mg, 2 mmoles) and pyridine (0.2 ml) in 5 ml of DMF was added phenyl chloroformate (400 mg, 2.5 mmoles), and the mixture was stirred at room temperature for 1.5 days. The crystalline precipitate was collected by filtration to afford 386 mg (71%) of the title compound. Mp. >290° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04500526 |
| Source dataset | uspto-grants-1985_02 |
| ORD ID | ord-90e061e55a7d4e729b9abc7088327d56 |
| Source note | uspto-grants-1985_02 |