HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dicyclohexylcarbodiimide → N-[(3-pyridyl)methyl]-N-(4-fluorophenyl)-alpha-(n-butylthio)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reactant | (Butylthio)acetic acid | HCID 88607 | — |
| Reactant | N-(4-Fluorophenyl)-3-pyridinemethanamine | HCID 645683 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | N-[(3-pyridyl)methyl]-N-(4-fluorophenyl)-alpha-(n-butylthio)acetamide | HCID 13652430 | — |
Reaction Steps
N-[(3-pyridyl)methyl]-N-(4-fluorophenyl)-α-(n-butylthio)acetamide was prepared by the method of Example 2 by reacting 10.1 g. of N-(4-fluorophenyl)-[(3-pyridyl)methyl]amine with 7.4 g. of α-(n-butylthio)acetic acid and 10.3 g. of N,N'-dicyclohexylcarbodiimide in 250 ml. of dichloromethane. Weight 6.5 g. as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04501746 |
| Source dataset | uspto-grants-1985_02 |
| ORD ID | ord-a5fb947f742b433fb5addfcae35a70de |
| Source note | uspto-grants-1985_02 |