HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dicyclohexylcarbodiimide → N-(3-pyridyl)-N-[(4-chlorophenyl)methyl]-alpha-(n-butylthio)acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dicyclohexylcarbodiimide | HCID 10868 | — |
| Reactant | (Butylthio)acetic acid | HCID 88607 | — |
| Reactant | N-(4-Chlorobenzyl)pyridin-3-amine | HCID 10036347 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | N-(3-pyridyl)-N-[(4-chlorophenyl)methyl]-alpha-(n-butylthio)acetamide | HCID 13652434 | — |
Reaction Steps
N-(3-pyridyl)-N-[(4-chlorophenyl)methyl]-α-(n-butylthio)acetamide was prepared by reacting 5.0 g. of N-(3-pyridyl)-[(4-chlorophenyl)methyl]amine with 3.5 g. of α-(n-butylthio)acetic acid and 5.0 g. of N,N'-dicyclohexylcarbodiimide in 100 ml. of dichloromethane according to the method of Example 2. Weight collected was 3.9 g as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04501746 |
| Source dataset | uspto-grants-1985_02 |
| ORD ID | ord-757d8eb17b524bae9ec53b7e29a69c27 |
| Source note | uspto-grants-1985_02 |