HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclooctylamine → 7-(2-Hydroxy-3-cyclooctylaminopropoxy)-isoflavone hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclooctylamine | HCID 2903 | — |
| Reactant | 7-(2,3-Epoxypropoxy)-3-phenylchromone | HCID 10108482 | — |
| Reactant | Ethanol hydrochloride | HCID 21887872 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | 7-(2-Hydroxy-3-cyclooctylaminopropoxy)-isoflavone hydrochloride | HCID 20406830 | — |
Reaction Steps
Using Method B, the reaction of 7-(2,3-epoxypropoxy)isoflavone with cyclooctylamine followed by acidification of the resulted free base with HCl/EtOH gave the hydrochloride as light yellow prisms, m.p. 185°-186° (iPrOH).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04501755 |
| Source dataset | uspto-grants-1985_02 |
| ORD ID | ord-774675ad157e41fdb4a0d7016dfe625b |
| Source note | uspto-grants-1985_02 |