反应详情

温度

20 °C

2.1 g of manganese dioxide were added to a mixture of 0.5 g of (2-benzyl-4-thiazolyl)-methanol and 10 ml of benzene and the mixture was stirred at 20° C. for 20 hours and was filtered. The filtrate was evaporated to dryness and the residue was chromatographed over silica gel. Elution with a 7-3 hexane-ethyl acetate mixture yielded 0.3 g of (2-benzyl-4-thiazolyl)-methanal melting at 78° C.

1. filtrationwas filtered
2. customThe filtrate was evaporated to dryness
3. customthe residue was chromatographed over silica gel
4. washElution with a 7-3 hexane-ethyl acetate mixture