Carbon Tetrachloride → HCID 20370601, compound

HRID 615978Notes

Reaction equation

HRID 615978 reaction equation
[CH3:1][N:2]([CH3:19])[C:3](=[O:18])[CH:4]([CH3:17])[N:5]1[C:9](C)=[CH:8][C:7]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)=[N:6]1.Cl[O:21][C:22](C)(C)C.BrBr.C(Cl)(Cl)(Cl)[Cl:29]>C(O)(=O)C>[Cl:29][C:8]1[C:7]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=2[O:21][CH3:22])=[N:6][N:5]([CH:4]([CH3:17])[C:3]([N:2]([CH3:19])[CH3:1])=[O:18])[CH:9]=1

Participants

6

Reactant 4

HCID 5943Carbon TetrachlorideHCID 24408BromineHCID 521297Tert-Butyl hypochloriteHCID 20370380N,N-Dimethyl-2-(5-methyl-3-phenyl-1H-pyrazol-1-yl)propanamide

Product 1

HCID 20370601HCID 20370601, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Following the procedure of Example 108, but substituting N,N,α-trimethyl-3-(o-methoxyphenyl)pyrazole-1-acetamide for N,N,α,5-tetramethyl-3-phenylpyrazole-1-acetamide, tert-butyl hypochlorite for bromine, and carbon tetrachloride for acetic acid as the reaction solvent, there was obtained 4-chloro-N,N,α-trimethyl-3-(o-methoxyphenyl)pyrazole-1-acetamide having a melting point of 74°-77° C.

Sources & evidence

ORD record
ord-2d34d407622340ccb9f538f8f0ae71b5
Source dataset
uspto-grants-1978_02
Patent number
US04072498

Reaction notes

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