2-Bromo-N,N,2-trimethylpropanamide → alpha-bromo-N,N,4-trimethyl-3-phenylpyrazole-1-propionamide

HRID 615982Notes

Reaction equation

HRID 615982 reaction equation
[Br:1][C:2]([CH3:9])(C)[C:3]([N:5]([CH3:7])[CH3:6])=[O:4].[CH3:10][C:11]1[C:12]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)=[N:13][NH:14][CH:15]=1.C1(C2C=CNN=2)C=CC=CC=1>>[Br:1][CH:2]([CH2:9][N:14]1[CH:15]=[C:11]([CH3:10])[C:12]([C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=2)=[N:13]1)[C:3]([N:5]([CH3:7])[CH3:6])=[O:4]

Participants

4

Reactant 3

HCID 124756442-Bromo-N,N,2-trimethylpropanamideHCID 178420101HCID 178420101, compoundHCID 178430907HCID 178430907, compound

Product 1

HCID 20370456alpha-bromo-N,N,4-trimethyl-3-phenylpyrazole-1-propionamide

Procedure

Following the procedure of Example 121, but substituting 2,3-dibromo-N,N-dimethylpropionamide for 2-bromo-N,N,2-trimethylpropionamide and 4-methyl-3-phenylpyrazole for 3-phenylpyrazole there was obtained α-bromo-N,N,4-trimethyl-3-phenylpyrazole-1-propionamide having a melting point of 104°-107° C.

Sources & evidence

ORD record
ord-5a4c6d064ed042f5a1501aaa3e98b3c4
Source dataset
uspto-grants-1978_02
Patent number
US04072498

Reaction notes

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