Propanamide, 2-chloro-N,N-dimethyl- → HCID 20370341, compound

HRID 615988Notes

Reaction equation

HRID 615988 reaction equation
Cl[CH:2]([CH3:8])[C:3]([N:5]([CH3:7])[CH3:6])=[O:4].[F:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[C:16]1[C:20]([CH3:21])=[CH:19][NH:18][N:17]=1.[CH3:22]C1C(C2C=CC=CC=2)=NNC=1>>[CH2:8]([CH:2]([N:18]1[CH:19]=[C:20]([CH3:21])[C:16]([C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=2[F:9])=[N:17]1)[C:3]([N:5]([CH3:7])[CH3:6])=[O:4])[CH3:22]

Participants

4

Reactant 3

HCID 112034Propanamide, 2-chloro-N,N-dimethyl-HCID 178430907HCID 178430907, compoundHCID 178430909HCID 178430909, compound

Product 1

HCID 20370341HCID 20370341, compound

Procedure

Using the procedure of Example 1, but substituting 2-bromo-N,N-dimethylbutyramide for 2-chloro-N,N-dimethylpropionamide and 3-(o-fluorophenyl)-4-methylpyrazole for 4-methyl-3-phenylpyrazole, there was obtained α-ethyl-3-(o-fluorophenyl)-N,N,4-trimethylpyrazole-1-acetamide, b.p. 171°-173° C./0.15 mm.

Sources & evidence

ORD record
ord-8c15278c32b846808e5a1ac66d7d3847
Source dataset
uspto-grants-1978_02
Patent number
US04072498

Reaction notes

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