Propanamide, 2-chloro-N,N-dimethyl- → HCID 20370453, compound

HRID 615989Notes

Reaction equation

HRID 615989 reaction equation
Cl[CH:2]([CH3:8])[C:3]([N:5]([CH3:7])[CH3:6])=[O:4].[Br:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[C:16]1[C:20]([CH3:21])=[CH:19][NH:18][N:17]=1.[CH3:22]C1C(C2C=CC=CC=2)=NNC=1>>[Br:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[C:16]1[C:20]([CH3:21])=[CH:19][N:18]([CH:2]([CH2:8][CH3:22])[C:3]([N:5]([CH3:7])[CH3:6])=[O:4])[N:17]=1

Participants

4

Reactant 3

HCID 112034Propanamide, 2-chloro-N,N-dimethyl-HCID 178430907HCID 178430907, compoundHCID 178430908HCID 178430908, compound

Product 1

HCID 20370453HCID 20370453, compound

Procedure

Using the procedure of Example 1, but substituting 2-bromo-N,N-dimethylbutyramide for 2-chloro-N,N-dimethylpropionamide and 3-(o-bromophenyl)-4-methylpyrazole for 4-methyl-3-phenylpyrazole, there was obtained 3-(o-bromophenyl)-α-ethyl-N,N,4-trimethylpyrazole-1acetamide, b.p. 188°-190° C./0.12 mm.

Sources & evidence

ORD record
ord-acaf406e2b2b4e9a982bb935099232ff
Source dataset
uspto-grants-1978_02
Patent number
US04072498

Reaction notes

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