Propanamide, 2-chloro-N,N-dimethyl- → HCID 20370340, compound

HRID 615990Notes

Reaction equation

HRID 615990 reaction equation
Cl[CH:2]([CH3:8])[C:3]([N:5]([CH3:7])[CH3:6])=[O:4].[C:9]1([C:15]2[C:19]([CH:20]([CH3:22])[CH3:21])=[CH:18][NH:17][N:16]=2)[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1.[CH3:23]C1C(C2C=CC=CC=2)=NNC=1>>[CH2:8]([CH:2]([N:17]1[CH:18]=[C:19]([CH:20]([CH3:22])[CH3:21])[C:15]([C:9]2[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=2)=[N:16]1)[C:3]([N:5]([CH3:7])[CH3:6])=[O:4])[CH3:23]

Participants

4

Reactant 3

HCID 112034Propanamide, 2-chloro-N,N-dimethyl-HCID 178430907HCID 178430907, compoundHCID 178439633HCID 178439633, compound

Product 1

HCID 20370340HCID 20370340, compound

Procedure

Using the procedure of Example 1, but substituting 2-bromo-N,N-dimethylbutyramide for 2-chloro-N,N-dimethylpropionamide and 3-phenyl-4-isopropylpyrazole for 4-methyl-3-phenylpyrazole, there was obtained α-ethyl-N,N-dimethyl-3-phenyl-4-isopropylpyrazole-1-acetamide, m.p. 89°-90° C.

Sources & evidence

ORD record
ord-387e783303a9427c8f57f142878e380f
Source dataset
uspto-grants-1978_02
Patent number
US04072498

Reaction notes

Loading…