HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → 4-[1-(Prop-2-en-1-yl)piperidin-3-yl]benzene-1,2-diol--hydrogen bromide (1/1)
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | 3-(3,4-Dimethoxyphenyl)-1-(prop-2-en-1-yl)piperidine | HCID 20370848 | — |
| Product | 4-[1-(Prop-2-en-1-yl)piperidin-3-yl]benzene-1,2-diol--hydrogen bromide (1/1) | HCID 3046381 | — |
Reaction Steps
A solution of 5.55 g of N-allyl-3-(3',4'-dimethoxyphenyl)-piperidine in 55 ml of 66% hydrobromic acid was refluxed for an hour and was evaporated to dryness. The residue was crystallized from isopropanol and then acetonitrile to obtain 3.27 g of N-allyl-3-(3',4'-dihydroxyphenyl)-piperidine hydrobromide melting at 235° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04072685 |
| Source dataset | uspto-grants-1978_02 |
| ORD ID | ord-b4a98ae2ab414694bf407412f16bec2a |
| Source note | uspto-grants-1978_02 |