Sodium Hydroxide → 4-[(Methoxymethyl)sulfanyl]-2-nitroaniline

HRID 616087Notes

Reaction equation

HRID 616087 reaction equation
C([NH:4][C:5]1[CH:10]=[CH:9][C:8]([S:11][CH2:12][O:13][CH3:14])=[CH:7][C:6]=1[N+:15]([O-:17])=[O:16])(=O)C.[OH-].[Na+]>CO>[NH2:4][C:5]1[CH:10]=[CH:9][C:8]([S:11][CH2:12][O:13][CH3:14])=[CH:7][C:6]=1[N+:15]([O-:17])=[O:16]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 20362834N-{4-[(Methoxymethyl)sulfanyl]-2-nitrophenyl}acetamide

Product 1

HCID 203628174-[(Methoxymethyl)sulfanyl]-2-nitroaniline

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

1.4 G. of 1-acetamido-2-nitro-4-methoxymethylthiobenzene is treated on a steam bath for 15 minutes with 3 ml. 5N sodium hydroxide and 6 ml. methanol. The mixture is concentrated, extracted with chloroform and the chloroform extracts dried and stripped yielding 1-amino-2-nitro-4-methoxymethylthiobenzene as a red solid.

Workup

  1. concentrationThe mixture is concentrated
  2. extractionextracted with chloroform
  3. dry with materialthe chloroform extracts dried

Sources & evidence

ORD record
ord-e7159faed451483baa1d0f059e33c05a
Source dataset
uspto-grants-1978_02
Patent number
US04072696

Reaction notes

Loading…