HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → 2-Nitro-5-phenylthioaniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Thiophenol | HCID 7969 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 5-Chloro-2-nitroaniline | HCID 74218 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-Nitro-5-phenylthioaniline | HCID 170737 | — |
Reaction Steps
2.53 G. 57% sodium hydride in oil suspension in 20 ml. dimethylformamide is treated with 6.2 ml. thiophenol under nitrogen. 5.0 G. 2-amino-4-chloro-1-nitrobenzene is added and the mixture stirred for three hours. Water is added and the product filtered off and washed with water and hexane. Recrystallization from methanol gives pure 2-amino-4-phenylthio-1-nitrobenzene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04072696 |
| Source dataset | uspto-grants-1978_02 |
| ORD ID | ord-5a63d8bc2d7d48a58bccc89211b60f8a |
| Source note | uspto-grants-1978_02 |