HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 4-[(Methylsulfanyl)methoxy]-2-nitroaniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | N-{4-[(Methylsulfanyl)methoxy]-2-nitrophenyl}acetamide | HCID 20362815 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Water | HCID 962 | — |
| Product | 4-[(Methylsulfanyl)methoxy]-2-nitroaniline | HCID 20362826 | — |
Reaction Steps
1.8 G. of 1 -acetamido-4-methylthiomethoxy-2-nitrobenzene is treated with sodium hydroxide in methanol, warmed briefly on a steam bath for about 15 minutes until the reaction is complete, diluted with water and extracted with dichloromethane to give 1-amino-4-methylthiomethoxy-2-nitrobenzene as a red oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04072696 |
| Source dataset | uspto-grants-1978_02 |
| ORD ID | ord-26002131e11c46b1b6d5ba160f5448a2 |
| Source note | uspto-grants-1978_02 |