HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 2-Nitro-4-phenoxyaniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | N-(2-nitro-4-phenoxy-phenyl)acetamide | HCID 3828525 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-Nitro-4-phenoxyaniline | HCID 5173752 | — |
Reaction Steps
1-Acetamido-2-nitro-4-phenoxybenzene is treated with 20 ml. methanol and 10 ml. 5 N aqueous sodium hydroxide at 20°-25° C for one hour. The mixture is diluted with water and the crude product filtered off. Recrystallization yields 1-amino-2-nitro-4-phenoxybenzene. This latter compound is treated in accordance with the first paragraph of Example VI to afford 1-(3-methoxycarbonyl-2-thioureido)-2-nitro-4-phenoxybenzene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04072696 |
| Source dataset | uspto-grants-1978_02 |
| ORD ID | ord-26aabde1758f433da668212e71bfbf78 |
| Source note | uspto-grants-1978_02 |