HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl chloroformate → 2-Nitro-4-phenylsulfinyl-1-(3-methoxycarbonyl-2-thioureido)benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl chloroformate | HCID 6586 | — |
| Reactant | Potassium thiocyanate | HCID 516872 | — |
| Reactant | Methoxycarbonyl isothiocyanate | HCID 552246 | — |
| Reactant | 2-Nitro-4-phenylsulfinylaniline | HCID 13166646 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 2-Nitro-4-phenylsulfinyl-1-(3-methoxycarbonyl-2-thioureido)benzene | HCID 20371142 | — |
Reaction Steps
2.6 G. of 2-nitro-4-phenylsulfinylaniline is dissolved in 25ml. of acetone and treated at 20°-25° C with 60 ml. of a solution of methoxycarbonyl isothiocyanate (made from 0.075 mol. (each) of potassium thiocyanate and methylchloroformate in acetone). After several days, the solvent is evaporated and the residue triturated with ether. Recrystallization from methanol-chloroform yields 2-nitro-4-phenylsulfinyl-1-(3-methoxycarbonyl-2-thioureido)benzene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04072696 |
| Source dataset | uspto-grants-1978_02 |
| ORD ID | ord-c8bcf54ac2974250bf7de2c28022ab16 |
| Source note | uspto-grants-1978_02 |