反应详情

1.5 G. of 2-nitro-4-phenysulfinyl-1-(3-methoxycarbonyl-2-thioureido)benzene is dissolved in a hot mixture of 450ml. of methanol and 200ml. of water. 15 G. of sodium hydrosulfite is added and, after boiling for 10 minutes, the solution is concentrated. The mixture is diluted with water, extracted thoroughly with chloroform and the product isolated by evaporation of the chloroform. Recrystallizing from methanol-chloroform yields 2-amino-1-(3-methoxycarbonyl-2-thioureido)-4-phenylsulfinylbenzene.

1. concentrationthe solution is concentrated
2. additionThe mixture is diluted with water
3. extractionextracted thoroughly with chloroform
4. customthe product isolated by evaporation of the chloroform
5. customRecrystallizing from methanol-chloroform