Acetic Anhydride → HCID 70619149, compound

HRID 616208Notes

Reaction equation

HRID 616208 reaction equation
[C:1]1([C:7]2([CH2:13][CH2:14][OH:15])[CH2:12][CH2:11][NH:10][CH2:9][CH2:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:16]1([C:22]([C:32]2[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=2)([C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[CH2:23][CH2:24][Cl:25])[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1.[C:38](OC(=O)C)(=[O:40])[CH3:39]>>[ClH:25].[C:16]1([C:22]([C:32]2[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=2)([C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[CH2:23][CH2:24][N:10]2[CH2:9][CH2:8][C:7]([C:1]3[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=3)([CH2:13][CH2:14][O:15][C:38](=[O:40])[CH3:39])[CH2:12][CH2:11]2)[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

4

Reactant 3

HCID 7918Acetic AnhydrideHCID 122374302-(4-PHENYLPIPERIDIN-4-YL)ETHANOLHCID 203569821,1',1''-(3-Chloropropane-1,1,1-triyl)tribenzene

Product 1

HCID 70619149HCID 70619149, compound

Procedure

Alternatively this compound is prepared by the reaction of 4-phenyl-4-piperidineethanol with 3,3,3-triphenylpropyl chloride, also as described in Example 1. Reaction with acetic anhydride by methods set out in Example 3 provides 1-(3,3,3-triphenylpropyl)-4-phenyl-4-acetoxyethylpiperidine hydrochloride.

Sources & evidence

ORD record
ord-1131de9ec0244a30bab7f45ebfa529cd
Source dataset
uspto-grants-1978_02
Patent number
US04072686

Reaction notes

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