HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-Aminodeacetoxycephalosporanic acid → Cephalexin
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-Aminodeacetoxycephalosporanic acid | HCID 33498 | — |
| Reactant | D-Phenylglycine methyl ester hydrochloride | HCID 12247453 | — |
| Product | Cephalexin | HCID 27447 | — |
Reaction Steps
The wet mycelium so obtained is suspended in M/30-phosphate buffer (pH 6.0), containing 7-aminodeacetoxycephalosporanic acid and D-α-phenylglycine methyl ester hydrochloride (0.4 g), at 28° C for 24 hours. The amount of Cefalexin formed in the reaction mixture is 0.095 g when determined by microbiological assay.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04073687 |
| Source dataset | uspto-grants-1978_02 |
| ORD ID | ord-a28de56108644757b01c0c05604cb9ff |
| Source note | uspto-grants-1978_02 |