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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 616227Generated: October 26, 2026

6-Aminopenicillanic acid → Ampicillin

https://huagongshe.com/reaction/616227

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Aminopenicillanic acidHCID 11082—
ReactantD-Phenylglycine methyl ester hydrochlorideHCID 12247453—
ProductAmpicillinHCID 6249—

Reaction Steps

Under the condition similar to that of Example 15, 6-aminopenicillanic acid is reacted with D-α-phenylglycine methyl ester hydrochloride using the mycelium obtained in the procedure of Example 15 to produce 0.08 g of Ampicillin when determined by microbiological assay.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04073687
Source datasetuspto-grants-1978_02
ORD IDord-1930c48330bf46d88313b3d4c52fd227
Source noteuspto-grants-1978_02