Ammonia → Pyridine
Reaction equation
[CH2:1]=[CH:2][CH:3]=[CH2:4].C=O.N.F.F.F[Si](F)(F)F.[N:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[CH3:1][C:2]1[CH:16]=[N:15][CH:20]=[CH:4][CH:3]=1.[N:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1Participants
Conditions
- Temperature
- 320 °C
Procedure
Following the same general procedure as in Example 1, a gaseous mixture of 1,3-butadiene (2.1% by volume), formaldehyde (1.7% by volume), ammonia (7.8% by volume), air 31.5% by volume), steam (33.2% by volume) and nitrogen (23.7% by volume) was passed through a fluidised bed of "Synclyst" catalyst (previously treated with fluosilicic acid in an amount corresponding to 5% by weight of the catalyst) maintained at 320° C. The contact time was 4.9 seconds and the mixture was passed over a period of 4 hours during which time 0.41 mole of 1,3-butadiene and 0.33 mole of formaldehyde were fed. 0.352 mole of unreacted butadiene was recovered corresponding to a molar conversion of 14.8%. A total of 0.027 mole of pyridine and 0.0055 mole of 3-methylpyridine were formed, corresponding to a pyridine yield of 44% of the butadiene consumed.
Sources & evidence
- ORD record
- ord-b3ed49ea32944ef1b9dbff8d801baf47
- Source dataset
- uspto-grants-1978_02
- Patent number
- US04073787
Reaction notes
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