HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl acetoacetate → Methyl 3-oxo-6-octenoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl acetoacetate | HCID 7757 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | (2E)-1-Chloro-2-butene | HCID 637923 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Product | Methyl 3-oxo-6-octenoate | HCID 6278738 | — |
Reaction Steps
In accordance with the process of Reference 1, sodium hydride (1.20 g; 50 m mol), methyl acetoacetate (5.70 g; 50 m mol), n-butyl lithium (50 m mol) and trans-crotyl chloride (4.43 g; 50 m mol) were used to obtain 3.60 g of (E)-3-oxo-6-octenoic acid methyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04073799 |
| Source dataset | uspto-grants-1978_02 |
| ORD ID | ord-28b444a48c3544e0a82859575db53c62 |
| Source note | uspto-grants-1978_02 |