化工社化工社 化学情報印刷レポート · 研究参考用
Benzyl mercaptan → 5-Benzylthiomethyl-2-oxo-cyclopentanecarboxylic acid methyl ester
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Benzyl mercaptan | HCID 7509 | — |
| 反応物 | Methyl heptanoate | HCID 7826 | — |
| 反応物 | Potassium tert-butoxide | HCID 23665647 | — |
| 生成物 | 5-Benzylthiomethyl-2-oxo-cyclopentanecarboxylic acid methyl ester | HCID 54031523 | 78% |
反応手順
In accordance with the process of Example 16, potassium t-butoxide (336 mg; 3 m mol), benzyl mercaptan (372 mg; 3 m mol) and 2-oxo-bicyclo 3.1.0! hexane-1-carboxylic acid methyl ester (463 mg; 3 m mol) were used in the reaction, and the reaction product was purified by a silica gel column chromatography with ethyl acetate and n-hexane (1.5; 8.5) to obtain 650 mg of 5-benzylthiomethyl-2-oxo-cyclopentanecarboxylic acid methyl ester as an oil.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04073799 |
| 出典データセット | uspto-grants-1978_02 |
| ORD ID | ord-9ddf21f58ffd4e66a86d7463b454d7de |
| 出典メモ | uspto-grants-1978_02 |