Potassium cyanate → HCID 53654800, compound

HRID 616338Notes

Reaction equation

HRID 616338 reaction equation
[O-:1][C:2]#[N:3].[K+].Cl.[OH:6][CH:7]([CH2:14][OH:15])[CH2:8][S:9]([CH2:11][CH2:12][NH2:13])=[O:10]>O>[OH:6][CH:7]([CH2:14][OH:15])[CH2:8][S:9]([CH2:11][CH2:12][NH:13][C:2]([NH2:3])=[O:1])=[O:10]

Participants

4

Reactant 2

HCID 11378442Potassium cyanateHCID 86735463HCID 86735463, compound

Product 1

HCID 53654800HCID 53654800, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
-5 °C

Procedure

There is slowly added to an aqueous solution of potassium cyanate (5 × 10-3 mole) a solution of 5 × 10-3 mole of 2-(2,3-dihydroxy propylsulfinyl) ethylamine hydrochloride in water. This mixture is agitated for 1 hour at a temperature lower than -5° C. The mixture is then concentrated under reduced pressure and the resulting residue is taken up in methanol and filtered. The filtrate is evaporated and the residue is crystallized in a mixture of isopropanol and acetonitrile, yielding white crystals having a melting point of 102° C.

Workup

  1. concentrationThe mixture is then concentrated under reduced pressure
  2. filtrationfiltered
  3. customThe filtrate is evaporated
  4. customthe residue is crystallized in a mixture of isopropanol and acetonitrile
  5. customyielding white crystals

Sources & evidence

ORD record
ord-9a4dadf4e4f74df9803e02dc47f4120b
Source dataset
uspto-grants-1978_02
Patent number
US04073898

Reaction notes

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