1-Bromo-2-Chloroethane → HCID 20369773, compound

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Reaction Steps

2,6-Bis(2-hydroxyethoxy)anthraquinone can be prepared as in (A) above by substituting 75 g. (0.60 mole) of 2-bromoethanol for 1-bromo-2-chloroethane. Then, with stirring, 25 g. of thionyl chloride is added to a mixture of 20 g. (0.06 mole) of the 2,6-bis(2-hydroxyethoxy)anthraquinone and 0.5 ml. of pyridine in 200 ml. of chloroform. The mixture is heated to reflux on a steam bath for six hours, after which the excess thionyl chloride and chloroform are removed under reduced pressure. The residue is dissolved in chloroform and the solution washed with saturated sodium bicarbonate solution and water, then dried with anhydrous magnesium sulfate. As in (A) above, the 2,6-bis(2-chloroethoxy) anthraquinone is isolated and recrystallized, if needed.

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